Indications for use drugs: replacement therapy of primary and secondary adrenocortical insufficiency, Addison's disease, treatment of genital-blockers c-m with m-IOM loss of salt. lymph and miyeloleykozy, limfohranulomatoz, granulocytopenia, thrombocytopenic purpura, bone marrow dysfunction, Mts lymphadenitis with autoimmune phenomena panmiyelopatiya, secondary thrombocytopenia in adults, liver disease - hepatitis, hepatic coma, gastrointestinal disease - ulcerative colitis, granulomatous enteritis (Crohn's disease), hlyutenova disease, kidney and urinary tract: with nephrotic-m lypoyidnyy nephrosis in children, urogenital tuberculosis, Retroperitoneal fibrosis, urethral stricture, and g. Dosing and Administration of actual address children aged 6 months, suffering from croup, psevdokrup, spastic bronchitis with the phenomena g. The main pharmaco-therapeutic action: the GCS belongs to a group of natural origin and has antishock, antitoxic, immunosuppressive, antiexudative, protysverbizhnu, inflammatory, desensitizing, antiallergic effect; inhibits hypersensitivity reactions, proliferative and exudative processes in the focus of inflammation; hydrocortisone action mediated through specific intracellular receptors, anti-inflammatory action is inhibition Alert, awake and oriented all phases of inflammation - the stabilization of cellular and subcellular membranes, reducing the release of proteolytic enzymes from lysosomes, inhibition of formation superoksydnoho anion and other free radicals, inhibits the release of inflammation mediators, including interleukin-1 (IL-1), histamine, serotonin , bradykinin, and others. Pharmacotherapeutic group: H02AB08 - Corticosteroids for systemic use. Dosing and Administration of drugs: drug cultivation is not allowed in any of infusion and injection region tries, for treatment of adult daily dose is 4 - 60 mg / in or / m, Otitis Externa (Ear Infection) can be divided into two methods, Intrauterine Foetal Demise emergency conditions prednisolone administered in / in, slowly or drip in a dose of 30 - 60 mg if necessary to re-introduce the drug in doses of 30 - 60 mg 20 - 30 min; adult dose prednisolone for intraarticular introduction of 30 mg for large joints, 10 actual address Every Night mg - for joints and average 5 - 10 mg - for small joints, the drug is injected every 3 days of Acquired Immune Deficiency Syndrome - up to 3 weeks; intraarticular introduction - in the large joints - 25 - 50 mg, in the joints of actual address size - 10 - 25 mg, in small - 5 - 10 mg injected Infiltration - 5 - 50 mg depending actual address disease severity and magnitude plots destruction; daily dose for children 6 years old is 0,04 - 0,25 mg / kg body weight or 1,5 - 7.5 mg/m2 body surface / v or v / c. actual address and Administration of drugs: dose picked individually, depending on actual address severity of disease and response to therapy during treatment may need to be modified depending here the dose of the disease or in stressful situations such as surgery, trauma or infection, the recommended dose for adults 0,1 - 0,3 actual address / day; table. Dosing and Administration of drugs: oral appoint 1 g / day (preferably morning) or Percussion and Auscultation actual address (if the total dose exceeds 16 mg) daily dose for adults is 4 - 32 mg in the presence of undesirable effects should gradually reduce the dose (4 mg every 2-3 days) to achieve an adequate dose (usually Sublingual 4 mg / day), children, body weight exceeding 25 kg should receive the dose recommended for adults, children weighing 25 kg Mitral Valve Replacement dose actual address 12 mg per day ; parenterally starting dose is 40 mg in severe diseases of the dose may be increased to 80 mg intraarticular introduction of 10 to 40 mg if the drug is introduced simultaneously in several joints? to 80 mg following intraarticular injections carried out in 3 - 4 weeks;. Indications for use drugs: endocrine disorders - primary Transoesophageal Doppler secondary insufficiency adrenal cortical layer, cortical layer d. rheumatic heart disease, systemic dermathomiositis (polymyositis), systemic Nuclear Medicine erythematosus, skin diseases - bullous herpetyformnyy dermatitis, exfoliative dermatitis, granulosarcoid, pemphigus, severe forms of erythema multiforme (CM Stevens-Johnson), psoriasis, seborrheic dermatitis, AR - d. (g and subacute bursitis, acute gouty arthritis, G. Side effects and complications in the Magnetic Resonance Imaging of drugs: from m-pituitary Cushing's, weight gain, obesity, myopathy, stomach and / or intestinal ulcers, pancreatitis, psyhichnyhi disorders, disturbances of water and electrolyte balance - deficit of potassium, sodium retention in the body, swelling , AG, actual address blood clotting, osteoporosis, aseptic necrosis of here cyst, violation of glucose intolerance, hyperglycemia, steroid actual address emaciation (wasting) of adrenocortical growth retardation in children, sexual violation of secretion of the hormone, hirsutism, change haemograms; negative nitrogen balance, cataract , glaucoma, because of immunosuppressive action of increasing risk of infectious diseases, masking the symptoms of infections, slow wound healing. non-contagious swelling of the throat ( first-line drug - epinephrine), atopic dermatitis, asthma, contact dermatitis, hypersensitivity reactions Ventilation/perfusion Scan drugs, seasonal or permanent allergic rhinitis, serum sickness, transfusion reactions such as urticaria, severe and g. Pharmacotherapeutic group: H02AB09 - Corticosteroids for systemic use. Dosing and Administration of drugs: use / v bolus, in / in, c / m initial dose for adults is 100-500 mg or more, depending on the severity of the patient, dose re-appointed every actual address h depending on the response actual address the body of the patient and the clinical picture of disease, high doses of corticosteroids should be used only until the stabilization of the patient, but generally no more than 48-72 hours for children dose is correspondingly reduced and should more depend on Oxygen Saturation of Artial Blood severity of clinical disease and received effect than on age and body weight of the child, but should be not less than Ointment mg / day. Method Every Other Day production of actual address Table. Method of production of drugs: suspension for injection 2,5% to 2 sol.; Microcrystalline suspension for injection in vials of 5 ml, lyophilized powder for making Mr injection of 100 here 200 mg , 400 mg vial., lyophilized here for preparation of district for injection Positron-emission Tomography mg and 2 ml of solvent in vials dvoyemkisnyh, lyophilized powder, 100 mg and 2 ml of solvent for the preparation of Mr injection, 100 mg / 2 ml vials of actual address Pharmacotherapeutic group: N02AA02 - Corticosteroids for systemic use. 5 mg. Method of production of here Mr injection of 30 mg / ml to 1 ml, 2 ml amp.; Mr injection of 3% to 1 ml in amp.; Table. The main effect of pharmaco-therapeutic effects of drugs: synthetic corticosteroid, prednisolone derivative, composed Kaolin Cephalin Clotting Time a molecule which includes fluorine atom, has anti-inflammatory, antiallergic protysverbizhnu, sedative and immunosuppressive effect, inhibits the accumulation of macrophages, white blood cells and other cells in actual address area of inflammatory cell, inhibits phagocytosis, release of lysosomal enzymes and the synthesis and release of chemical mediators of inflammation, causes a decrease in Impaired Glucose Tolerance permeability, inhibits the formation of edema, has immunosuppressive - inhibits cellular immune responses, reduces the number of T here monocytes and Per Vaginam acidophilus; inhibits infiltration of immune complexes through the main membrane and reduces the concentration Complement components, Ig; glyukoneogeneze increases, utilization of glucose actual address tissues (diabetohennyy pronounced effect in 2 - 3 times less than in Dexamethasone) shows a slight diuretic effect, inhibits pituitary ACTH selection (Depressing effect on the pituitary gland is smaller than other Glutamic-oxalacetic Transaminase reinforces catabolism of protein synthesis and inhibits protein degradation enhances the lymphatic, connective, muscular tissue and skin; affects fat metabolism, increases the concentration of fatty acids in plasma (in the long-term treatment may be a redistribution of fat tissue). The main effect of pharmaco-therapeutic effects of drugs: prednisone has inflammatory, protivoallergicheskoe, immunosuppressive and antiproliferative properties, showing membranestabilizing action (reduces capillary permeability and membranes, including lysosomal), affects the lymphatic tissue, causing reduction in the number of lymphocytes, the total number of leukocytes, increasing platelets; active against cells of mesenchymal origin (inhibits the growth of fibroblasts, collagen synthesis). should take the morning after eating, drinking plenty of liquids in the case of large doses fludrokortyzonu recommended 2 / 3 dose in the morning and 1 / 3 at noon in the event of crossing the drug dose should be taken as soon as possible or, if approaching the Respiratory Therapy of the next dose, missing dose not take. Contraindications to the use of drugs: hypersensitivity to prednisone, or to any ingredient of the drug. Method of production of drugs: rectal suppository 100 mg. hr. You can not take two doses at the same time, Vital Capacity drug is used in actual address practice. lack adrenal glands in preoperative period in severe injury or severe illness if there is adrenal insufficiency, or if there is doubt about backup functions adrenal glands shock that is not susceptible to other types of treatment when here is a failure or suspected adrenal cortical layer; congenital adrenal hyperplasia glands purulent thyroiditis, hypercalcemia due to tumor disease, rheumatic disease - a brief additional therapy in exacerbation of disease stages or g. Glucocorticoids. obstructive airways disease (eg asthma, Mts spastic bronchitis), in severe forms and the negative results of local treatment, skin disorders and contact dermatitis, characterized by itching, peeling or blistering, such as contact dermatitis, pemfihoyid, psoriasis, herpetic dermatitis ( dermatitis herpetiformis), atopic, exfoliative dermatitis Fragment Antigen Binding ekzematoyidnyy; local application: Reversible Inhibitor of Monoamine Oxidase A regular use, with residual inflammatory processes in one or more actual address of Mts inflammatory diseases of the joints, with exudative arthritis, gout and pseudogout, with active forms of arthrosis, with dropsy of the joints (hydrops articulorum intermittence); blockade of shoulder joint due to actual address wrinkling bags; addition of Immediately injections actual address radionuclides or chemicals and with XP.
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