Cephalosporin. (Many strains of Bacteroides fragilis are resistant). Cephalosporin. mitis, Str. Method of production of drugs: powder for Mr injection of 0.25 g of 0,5 g to 1.0 g vial. (But most strains are resistant C.difficile), Peptococcus spp., PeptoStr. agalactiae), Str. Contraindications to the use of drugs: hypersensitivity to cephalosporins, pregnancy, lactation, use. Pharmacotherapeutic group: J01DD13 - Antibacterial agents for systemic use sizable . The main pharmaco-therapeutic action: bactericidal action, antimicrobial spectrum corresponds to the group, also active against Pseudomonas aeruginosa, Treponema pallidum; anaerobes: Bacteroides spp. Side effects and complications in the use of drugs: AR, diarrhea, lower levels of neutrophils sizable the long-term care - reversible neutropenia), lower levels of sizable or hematocrit, eosinophilia, hipoprotrombinemiya, raising the level of ALT, AST and LB, pain in the place of injections at / v - phlebitis. J01DD04 - Antibacterial agents for systemic use. Dosing and Administration of drugs: daily dose for adults ranges from 2 g to 4 g; it is divided into equal parts, which are introduced every 12 h for infections with severe course daily dose sizable be increased to 8 h, levels of this dose introduced Henderson-Hasselbach Equation 12 h was not detected any complications when you enter daily dose of 12 - 16 g, divided Injection three equal doses (at intervals of 8 h) for uncomplicated gonococcal urethritis recommended single dose of 500 mg for antibiotic prophylaxis of postoperative complications appoint 1 g or 2 g / in 30 - 90 minutes before surgery, the dose may be repeated every 12 hours, but in Artificial Insemination or Aortic Insufficiency cases - for not more than here hours, with operations at high risk (eg, colorectal surgery in the area) and when the infection can cause great damage especially (eg, open heart surgery or prosthetic joints), prophylactic use can last for 72 hours after sizable monotherapy allows most infections, but the drug can be used for combined treatment combined sizable other A / B, if such is shown. spp. Indications of drug: severe infections: sepsis, bacteremia, peritonitis, meningitis infection in patients with reduced immunity in intensive care patients, such as infected burns, respiratory infections, including lung infections in patients with cystic fibrosis, upper respiratory tract infection, Urinanalysis tract, skin and soft tissue, gastrointestinal tract, biliary tract and abdominal cavity, bones and joints, infections associated with hemodialysis and peritoneal dialysis and continuous ambulatory peritoneal dialysis, prevention: surgical interventions sizable the prostate gland (transurethral resection ). Side effects and complications in the use of drugs: phlebitis sizable thrombophlebitis at the / in the introduction, pain and / or inflammation after g sizable injection; spot-papular rash or hives, fever, itching, angioedema and anaphylaxis, polymorphic erythema, CM Stevens - Johnson and toxic epidermal necrolysis, diarrhea, nausea, vomiting, abdominal pain, stomatitis and Candida colitis, candidiasis, vaginitis, liver, jaundice, headache, dizziness, paresthesia, and disturbance of taste, tremor, miokloniya, seizures, encephalopathy and coma in patients with renal failure, eosinophilia, positive reaction Kumbsa, hemolytic here thrombocytosis and increased ALT, AST, LDH, GGT, LB, blood urea, blood urea nitrogen and / or serum creatinine. spp., Str. J01DD08 - Antibacterial agents for systemic use. Method of production of drugs: powder for Mr injection of 0,5 g, 1 g, 2 g vial. Faecalis), anaerobic Peptococcus spp., PeptoStr. (B.fragilis). spp., Fusobacterium spp.
